BDBM50380148 CHEMBL2011156::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 6
SMILES NS(=O)(=O)c1ccc(cc1)C(=O)CSc1ncccn1
InChI Key InChIKey=GQFCFNQXNFZIFC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380148
Affinity DataKoff: 1.60E+6s-1Assay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli assessed as association rate constant after 30 secs by surface plasmon resona...More data for this Ligand-Target Pair
Affinity DataKon: 0.00800M-1s-1Assay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli assessed as dissociation rate constant after 30 secs by surface plasmon reson...More data for this Ligand-Target Pair
Affinity DataKd: 5.20nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.10nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-2 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity to human recombinant carbonic anhydrase-2 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.00800M-1s-1Assay Description:Binding affinity to human full length His-tagged CA2 (1 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as dissociation rate consta...More data for this Ligand-Target Pair
Affinity DataKd: 0.0170nMAssay Description:Binding affinity to human full length His-tagged CA2 (1 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic thermodynamic ...More data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair